Description

2-Amino-4-(4-Bromophenyl)-7,7-Dimethyl-1-(4-Methylphenyl)-5-Oxo-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex polycyclic quinoline structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling research and development in targeted therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct complex nitrogen-containing heterocycles due to its reactive amino and nitrile functional groups.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Academic & Industrial R&D: Utilized in exploratory research for developing new synthetic methodologies and novel compound libraries for high-throughput screening.

Basic Information

Product Name	2-Amino-4-(4-Bromophenyl)-7,7-Dimethyl-1-(4-Methylphenyl)-5-Oxo-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile
CAS No.	311323-36-1
Molecular Formula	C25H24BrN3O
Molecular Weight	462.38 g/mol
Synonyms	2-Amino-4-(4-bromophenyl)-7,7-dimethyl-1-(p-tolyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile; 1,4,5,6,7,8-Hexahydro-2-amino-4-(4-bromophenyl)-7,7-dimethyl-1-(4-methylphenyl)-5-oxo-3-quinolinecarbonitrile; 3-Quinolinecarbonitrile, 2-amino-4-(4-bromophenyl)-1,4,5,6,7,8-hexahydro-7,7-dimethyl-1-(4-methylphenyl)-5-oxo-; CAS 311323-36-1; Hexahydroquinolinecarbonitrile derivative; Bromophenyl Dimethylquinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Bromophenyl)-7,7-Dimethyl-1-(4-Methylphenyl)-5-Oxo-1,4,5,6,7,8-Hexahydro-3-Quinolinecarbonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.