Description

7-(Trifluoromethyl)-5,6-Dihydrobenzo[H]Pyrazolo[5,1-B]Quinazoline-10-Carboxylic Acid CAS NO 310451-85-5 is a high-value, multi-cyclic heteroaromatic compound featuring a trifluoromethyl group, a key structural motif prized for its ability to modulate the physicochemical properties of advanced molecules. This compound matters as a sophisticated pharmaceutical intermediate or research chemical, enabling the development of novel active ingredients with enhanced metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate this unique fused-ring scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a potential electron-transport or host material precursor due to its rigid, conjugated heterocyclic structure.
• Academic & Contract Research: Employed in medicinal chemistry programs and structure-activity relationship (SAR) studies to explore new chemical space.
• Fluorescent Probe Development: Utilized as a core structure for creating specialized dyes or sensors in biochemical and diagnostic applications.
• Chemical Biology Tool Compound: Investigated for use as a molecular scaffold or inhibitor in probing biological pathways and protein functions.

Basic Information

Product Name	7-(Trifluoromethyl)-5,6-Dihydrobenzo[H]Pyrazolo[5,1-B]Quinazoline-10-Carboxylic Acid
CAS No.	310451-85-5
Molecular Formula	C19H10F3N3O2
Molecular Weight	369.30 g/mol
Synonyms	7-(Trifluoromethyl)-5,6-dihydrobenzo[h]pyrazolo[5,1-b]quinazoline-10-carboxylic acid; 7-(Trifluoromethyl)-5,6-dihydrobenzo[h]pyrazolo[5,1-b]quinazoline-10-carboxylic acid; 310451-85-5; 7-Trifluoromethyl-5,6-dihydrobenzo[h]pyrazolo[5,1-b]quinazoline-10-carboxylic acid; Benzo[h]pyrazolo[5,1-b]quinazoline-10-carboxylic acid, 5,6-dihydro-7-(trifluoromethyl)-; SCHEMBL21842227; BCP31943; ZINC000253899577
EINECS	Contact for details

Quality Control

Our production of 7-(Trifluoromethyl)-5,6-Dihydrobenzo[H]Pyrazolo[5,1-B]Quinazoline-10-Carboxylic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified via advanced analytical techniques including HPLC, NMR, and LC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is stable under these conditions but should be kept away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.