Description

Methyl 4-Oxo-3-Prop-2-Enyl-2-Sulfanylidene-1H-Quinazoline-7-Carboxylate CAS NO 310448-90-9 is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazolinone-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• API Development: Serves as a core scaffold for developing potential kinase inhibitors and other targeted therapies.
• Chemical Synthesis: Employed in organic synthesis for constructing complex heterocyclic systems with potential biological activity.
• Biochemical Research: Utilized as a reference standard or probe compound in biochemical assays.

Basic Information

Product Name	Methyl 4-Oxo-3-Prop-2-Enyl-2-Sulfanylidene-1H-Quinazoline-7-Carboxylate
CAS No.	310448-90-9
Molecular Formula	C14H12N2O3S
Molecular Weight	288.32 g/mol
Synonyms	Methyl 4-oxo-3-(prop-2-en-1-yl)-2-sulfanylidene-1,2-dihydroquinazoline-7-carboxylate; 7-Quinazolinecarboxylic acid, 1,2-dihydro-4-oxo-3-(2-propen-1-yl)-2-thioxo-, methyl ester; 3-Allyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one-7-carboxylic acid methyl ester; Methyl 3-allyl-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylate; Allylthioquinazolinone methyl ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Methyl 4-Oxo-3-Prop-2-Enyl-2-Sulfanylidene-1H-Quinazoline-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.