Description

Benzene, 1-(Cyclopropyloxy)-3-Fluoro- (9Ci) is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. This compound matters for its unique structural motif, combining a cyclopropyl ether linkage with a fluorine substituent on the benzene ring, which is valuable for modulating the physicochemical properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly where fluorine and cyclopropyl groups are used to fine-tune metabolic stability, lipophilicity, and receptor binding.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides, leveraging the bioactivity often imparted by fluorinated aromatic structures.
• Material Science Research: Used in the synthesis of specialty monomers or ligands for advanced polymers, liquid crystals, or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or biological pathways.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the presence of reactive sites on the aromatic ring.

Basic Information

Product Name	Benzene, 1-(Cyclopropyloxy)-3-Fluoro- (9Ci)
CAS No.	309977-71-7
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	1-Fluoro-3-(cyclopropyloxy)benzene; 3-Fluorophenyl cyclopropyl ether; m-Fluorophenyl cyclopropyl ether; Cyclopropyl 3-fluorophenyl ether; 3-(Cyclopropyloxy)fluorobenzene; 3-Fluoro-1-(cyclopropyloxy)benzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-(Cyclopropyloxy)-3-Fluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.