Description

Methyl 3-Acetyl-6-Methyl-2-Oxo-4-[3-(Phenyloxy)Phenyl]-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, process chemistry, and scale-up production.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of target drug molecules, especially in medicinal chemistry programs.
• API Development: Used in research and development for constructing complex tetrahydropyrimidine-based active pharmaceutical ingredients.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling production from laboratory to pilot and commercial scales.
• Chemical Research: Acts as a specialized reagent in academic and industrial research for exploring new heterocyclic compounds and reaction methodologies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Methyl 3-Acetyl-6-Methyl-2-Oxo-4-[3-(Phenyloxy)Phenyl]-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	309293-61-6
Molecular Formula	C21H20N2O5
Molecular Weight	380.40 g/mol
Synonyms	Methyl 3-acetyl-6-methyl-2-oxo-4-(3-phenoxyphenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 4-(3-Phenoxyphenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid methyl ester derivative; 309293-61-6; DHPM derivative; Biginelli reaction product; Tetrahydropyrimidine-5-carboxylate ester; 3-Acetyl-4-(3-phenoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Acetyl-6-Methyl-2-Oxo-4-[3-(Phenyloxy)Phenyl]-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.