Description

2-(Hydroxymethyl)-2-Phenyl-2,3-Dihydro-4(1H)-Quinazolinone is a specialized quinazolinone derivative, a heterocyclic scaffold of significant interest in advanced organic synthesis. This compound matters as a versatile and valuable building block for pharmaceutical research and development, enabling the construction of complex molecules with potential biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Agrochemical Research: Serves as a building block for synthesizing new herbicides, fungicides, or insecticides with optimized efficacy and environmental profiles.
• Chemical Biology Probe Development: Used to create tool compounds for studying enzyme function and biological pathways, leveraging the quinazolinone core's ability to interact with various protein targets.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique thermal or optical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic chemistry and the discovery of new chemical entities.

Basic Information

Product Name	2-(Hydroxymethyl)-2-Phenyl-2,3-Dihydro-4(1H)-Quinazolinone
CAS No.	308832-66-8
Molecular Formula	C15H14N2O2
Molecular Weight	254.28 g/mol
Synonyms	2-(Hydroxymethyl)-2-phenyl-1,2,3,4-tetrahydroquinazolin-4-one; 2-Phenyl-2-(hydroxymethyl)-2,3-dihydro-4(1H)-quinazolinone; 2,3-Dihydro-2-(hydroxymethyl)-2-phenyl-4(1H)-quinazolinone; 4(1H)-Quinazolinone, 2,3-dihydro-2-(hydroxymethyl)-2-phenyl-; Quinazolinone derivative CAS 308832-66-8
EINECS	Contact for details

Quality Control

Our 2-(Hydroxymethyl)-2-Phenyl-2,3-Dihydro-4(1H)-Quinazolinone is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are available upon request. We support development projects with custom purity grades and specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.