Description

5-Nitro-2-(Trifluoromethoxy)Benzoic Acid is a high-purity, multifunctional aromatic building block characterized by its nitro and trifluoromethoxy substituents, which confer unique electronic and steric properties. This compound is essential for advanced organic synthesis, particularly in the development of complex molecules where precise functional group manipulation is required. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging its unique halogenated structure.
• Ligand and Catalyst Development: Serves as a sophisticated building block for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals, where its aromatic core and substituents modify material properties.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and tags to study biological processes.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, complex benzoic acid derivatives.

Basic Information

Product Name	5-Nitro-2-(Trifluoromethoxy)Benzoic Acid
CAS No.	307989-55-5
Molecular Formula	C8H4F3NO5
Molecular Weight	251.12 g/mol
Synonyms	2-(Trifluoromethoxy)-5-nitrobenzoic acid; Benzoic acid, 5-nitro-2-(trifluoromethoxy)-; 5-Nitro-2-trifluoromethoxybenzoic acid; 5-Nitro-α,α,α-trifluoro-o-anisic acid; 2-Trifluoromethoxy-5-nitrobenzoic acid; 5-Nitro-2-(trifluoromethoxy)benzoic acid; 307989-55-5
EINECS	Contact for details

Quality Control

Our 5-Nitro-2-(Trifluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.