Description

6-Bromo-4-Morpholin-4-Ylquinazoline is a high-purity, advanced pharmaceutical intermediate characterized by its distinct quinazoline core functionalized with bromine and morpholine groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of targeted kinase inhibitors and other bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in oncology and inflammatory disease research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of targeted small-molecule drugs, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns for novel drug candidates.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific enzyme functions and signaling pathways.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	6-Bromo-4-Morpholin-4-Ylquinazoline
CAS No.	307538-52-9
Molecular Formula	C₁₂H₁₂BrN₃O
Molecular Weight	294.15 g/mol
Synonyms	4-(6-Bromoquinazolin-4-yl)morpholine; 6-Bromo-4-morpholinoquinazoline; Quinazoline, 6-bromo-4-(4-morpholinyl)-; 307538-52-9; 4-Morpholino-6-bromoquinazoline; 6-Bromo-4-(morpholin-4-yl)quinazoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Morpholin-4-Ylquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.