Description

4-Chloro-6-Methoxy-7-(Phenylmethoxy)-3-Quinolinecarboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the quinoline class. It is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries seeking to produce novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, particularly those with a quinoline core structure.
• API Synthesis: Used in the research and commercial production of Active Pharmaceutical Ingredients (APIs) for potential therapeutic applications.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Fine Chemical Production: Employed in the manufacture of specialty and high-value fine chemicals requiring specific functionalization on the quinoline ring system.
• Chemical Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	4-Chloro-6-Methoxy-7-(Phenylmethoxy)-3-Quinolinecarboxylic Acid Ethyl Ester
CAS No.	307353-90-8
Molecular Formula	C20H18ClNO4
Molecular Weight	371.81 g/mol
Synonyms	Ethyl 4-Chloro-6-methoxy-7-(benzyloxy)quinoline-3-carboxylate; 7-(Benzyloxy)-4-chloro-6-methoxyquinoline-3-carboxylic Acid Ethyl Ester; 4-Chloro-6-methoxy-7-benzyloxyquinoline-3-carboxylic Acid Ethyl Ester; 307353-90-8; Quinoline-3-carboxylic acid, 4-chloro-6-methoxy-7-(phenylmethoxy)-, ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Methoxy-7-(Phenylmethoxy)-3-Quinolinecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.