Description

5-[Chloro(Difluoro)Methyl]-3-Methyl-n-[3-(Trifluoromethyl)Phenyl]-1H-Pyrazole-1-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated pyrazole-carboxamide structure. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development pipelines targeting specialized therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers seeking to develop new molecules with enhanced biological activity and selectivity.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a precursor for developing novel pesticides and herbicides, leveraging its halogenated structure for potential bioactivity.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and protein-ligand interactions due to its specific molecular scaffold.
• Material Science: Potential intermediate for creating specialty polymers or coatings with unique fluorinated properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	5-[Chloro(Difluoro)Methyl]-3-Methyl-n-[3-(Trifluoromethyl)Phenyl]-1H-Pyrazole-1-Carboxamide
CAS No.	306979-30-6
Molecular Formula	C14H10ClF5N3O
Molecular Weight	366.70 g/mol
Synonyms	5-[(Chlorodifluoromethyl]-3-methyl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]pyrazole; 3-Methyl-5-(chlorodifluoromethyl)-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-1-carboxamide; 306979-30-6; 5-(Chlorodifluoromethyl)-3-methyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-1-carboxamide; 1H-Pyrazole-1-carboxamide, 5-(chlorodifluoromethyl)-3-methyl-N-[3-(trifluoromethyl)phenyl]-; 5-(Chlorodifluoromethyl)-3-methyl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]pyrazole
EINECS	Contact for details

Quality Control

Our 5-[Chloro(Difluoro)Methyl]-3-Methyl-n-[3-(Trifluoromethyl)Phenyl]-1H-Pyrazole-1-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical and agrochemical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.