Description

2-(3,4-Dichlorophenyl)-3-Hydroxy-4(3H)-Quinazolinone CAS NO 306979-14-6 is a high-purity, synthetically derived quinazolinone derivative, serving as a critical advanced pharmaceutical intermediate and a versatile scaffold in medicinal chemistry research. Its core value lies in enabling the development of novel therapeutic agents, particularly for applications in oncology and neurology, by providing a structurally complex and functionalized building block. This compound is essential for R&D chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Oncology Drug Development: Used in the research and synthesis of potential anti-cancer agents due to the bioactive quinazolinone core.
• Neurological Disorder Research: Intermediate in the development of compounds for central nervous system (CNS) targets.
• Enzyme Inhibitor Synthesis: Precursor for molecules designed to inhibit kinases and other critical enzymes.
• Fine Chemical Synthesis: Used in custom synthesis and contract manufacturing for specialized chemical entities.
• Reference Standard: Serves as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	2-(3,4-Dichlorophenyl)-3-Hydroxy-4(3H)-Quinazolinone
CAS No.	306979-14-6
Molecular Formula	C14H8Cl2N2O2
Molecular Weight	307.13 g/mol
Synonyms	3-Hydroxy-2-(3,4-dichlorophenyl)-4(3H)-quinazolinone; 2-(3,4-Dichlorophenyl)-3-hydroxyquinazolin-4(3H)-one; 4(3H)-Quinazolinone, 2-(3,4-dichlorophenyl)-3-hydroxy-; Quinazolinone derivative 306979-14-6; 3-Hydroxy-2-(3,4-dichlorophenyl)-4-quinazolinone; 2-(3,4-Dichlorophenyl)-3-hydroxy-1,4-dihydro-4-oxoquinazoline
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dichlorophenyl)-3-Hydroxy-4(3H)-Quinazolinone is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.