Description

5-Nitrospiro[Benzimidazole-2,1'-Cyclopentane] 1,3-Dioxide is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic benzimidazole structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic frameworks. Pharmaceutical R&D teams and fine chemical manufacturers need this specialized intermediate to develop next-generation drugs targeting a range of conditions.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel benzimidazole-derived active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in research and development for constructing complex spirocyclic and fused heterocyclic compounds.
• Agrochemical Research: Serves as a key scaffold in the development of new fungicides or herbicides with specific modes of action.
• Material Science: Potential application in the development of specialty chemicals, dyes, or photoactive materials.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	5-Nitrospiro[Benzimidazole-2,1'-Cyclopentane] 1,3-Dioxide
CAS No.	306935-59-1
Molecular Formula	C12H11N3O4
Molecular Weight	261.24 g/mol
Synonyms	5-Nitrospiro[benzimidazole-2,1'-cyclopentane] 1,3-dioxide; 5-Nitro-1H,1'H-spiro[benzimidazole-2,1'-cyclopentane] 3-oxide; 5-Nitro-1H-spiro[cyclopentane-1,2'-benzimidazole] 3-oxide; Spiro[cyclopentane-1,2'-benzimidazole]-5-nitro-1',3-dioxide; 306935-59-1; 5-Nitro-spiro(cyclopentane-1,2'-benzimidazole)-1',3-dioxide
EINECS	Contact for details

Quality Control

Our 5-Nitrospiro[Benzimidazole-2,1'-Cyclopentane] 1,3-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.