Description

2-[(4-Methyl-5-Quinolin-6-Yl-4H-1,2,4-Triazol-3-Yl)Thio]Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular architecture combining quinoline and triazole pharmacophores. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex disease pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of next-generation therapeutics, including potential anticancer and antimicrobial agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of novel drug candidates, especially in oncology and anti-infective therapeutic areas.
• Biochemical Research: Used as a specialized reagent for studying enzyme inhibition and receptor-ligand interactions due to its heterocyclic structure.
• Agrochemical Development: Acts as a potential intermediate in the creation of new crop protection agents with specific biological activity.
• Material Science Research: Investigated for its utility in synthesizing functional organic materials and metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-purity, complex heterocyclic compounds.

Basic Information

Product Name	2-[(4-Methyl-5-Quinolin-6-Yl-4H-1,2,4-Triazol-3-Yl)Thio]Acetic Acid
CAS No.	306935-49-9
Molecular Formula	C₁₄H₁₂N₄O₂S
Molecular Weight	300.34 g/mol
Synonyms	2-[(4-Methyl-5-(quinolin-6-yl)-4H-1,2,4-triazol-3-yl)thio]acetic acid; 2-({4-Methyl-5-[6-quinolyl]-4H-1,2,4-triazol-3-yl}sulfanyl)acetic acid; 6-(4-Methyl-3-((carboxymethyl)thio)-4H-1,2,4-triazol-5-yl)quinoline; Acetic acid, 2-[(4-methyl-5-quinolin-6-yl-4H-1,2,4-triazol-3-yl)thio]-; CAS 306935-49-9
EINECS	Contact for details

Quality Control

Our 2-[(4-Methyl-5-Quinolin-6-Yl-4H-1,2,4-Triazol-3-Yl)Thio]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and compliance assurance for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.