Description

4-Methyl-5-Quinolin-6-Yl-4H-1,2,4-Triazole-3-Thiol is a specialized heterocyclic organic compound featuring a fused quinoline and 1,2,4-triazole scaffold with a thiol functional group. This unique molecular architecture makes it a valuable advanced intermediate for the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry and fine chemical production.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the development of novel drug candidates, particularly those targeting neurological disorders, cancers, and infectious diseases.
• Agrochemical Research: Used in the synthesis of new-generation pesticides, herbicides, and fungicides due to its bioactive heterocyclic core.
• Ligand Synthesis: The thiol and nitrogen-rich structure makes it a potential precursor for creating chelating ligands in catalysis and material science.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme inhibition and protein interactions.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique electronic or thermal properties.

Basic Information

Product Name	4-Methyl-5-Quinolin-6-Yl-4H-1,2,4-Triazole-3-Thiol
CAS No.	306935-38-6
Molecular Formula	C₁₂H₁₀N₄S
Molecular Weight	242.30 g/mol
Synonyms	6-(3-Mercapto-5-methyl-4H-1,2,4-triazol-4-yl)quinoline; 4-Methyl-5-(quinolin-6-yl)-4H-1,2,4-triazole-3-thiol; 5-(6-Quinolyl)-4-methyl-4H-1,2,4-triazole-3-thiol; 306935-38-6; 4-Methyl-5-quinolin-6-yl-1,2,4-triazole-3-thiol; 4-Methyl-5-(6-quinolyl)-1,2,4-triazol-3-thiol
EINECS	Contact for details

Quality Control

Every batch of our 4-Methyl-5-Quinolin-6-Yl-4H-1,2,4-Triazole-3-Thiol is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, the container should be purged with inert gas after each opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.