Description

2-[3-Isopropyl-5-(4-Methyl-1,3-Thiazol-2-Yl)-2,6-Dioxo-1,2,3,6-Tetrahydropyrimidin-1-Yl]Ethanohydrazide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in medicinal chemistry, enabling the development of targeted therapeutics with specific biological activity. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing next-generation drugs, particularly in areas like oncology and virology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting specific enzymes or receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• API Development: Serves as a core scaffold for the development of proprietary active pharmaceutical ingredients, particularly in antiviral or anticancer research.
• Biochemical Research: Employed as a tool compound or ligand in biochemical assays to study protein-ligand interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	2-[3-Isopropyl-5-(4-Methyl-1,3-Thiazol-2-Yl)-2,6-Dioxo-1,2,3,6-Tetrahydropyrimidin-1-Yl]Ethanohydrazide
CAS No.	306935-29-5
Molecular Formula	C13H17N5O3S
Molecular Weight	323.37 g/mol
Synonyms	2-[3-Isopropyl-5-(4-methyl-1,3-thiazol-2-yl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-1-yl]acetohydrazide; 2-(3-Isopropyl-5-(4-methylthiazol-2-yl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-1-yl)acetohydrazide; Ethanohydrazide, 2-[3-(1-methylethyl)-5-(4-methyl-2-thiazolyl)-2,6-dioxo-1,2,3,6-tetrahydro-1-pyrimidinyl]-; 306935-29-5; 2-(3-Isopropyl-5-(4-methylthiazol-2-yl)-2,6-dioxopyrimidin-1(6H)-yl)acetohydrazide
EINECS	Contact for details

Quality Control

Our 2-[3-Isopropyl-5-(4-Methyl-1,3-Thiazol-2-Yl)-2,6-Dioxo-1,2,3,6-Tetrahydropyrimidin-1-Yl]Ethanohydrazide is manufactured under strict quality management systems. Products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all specifications and test results. We support development and commercial projects with material suitable for research use and can supply grades aligned with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark place to maintain stability and prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.