Description

8-Sulfanyl-5-Quinolinesulfonic Acid Hemihydrate is a specialized heterocyclic sulfonic acid derivative with significant utility as a key intermediate in fine chemical synthesis. Its value lies in its unique bifunctional structure, which allows for selective chemical modifications, making it a critical building block for advanced materials and active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial and anticancer research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the quinoline scaffold provides specific biological activity.
• Dye and Pigment Manufacturing: Acts as a key intermediate for producing sulfonated quinoline dyes, which offer excellent color fastness and solubility.
• Chemical Research & Development: Employed as a versatile building block in organic synthesis for creating complex molecules with tailored properties.
• Coordination Chemistry: Functions as a ligand for metal ions, useful in catalysis and the preparation of metal-organic frameworks (MOFs).
• Analytical Reagent: Potential use in analytical chemistry as a derivatization agent or a component in sensor technologies.

Basic Information

Product Name	8-Sulfanyl-5-Quinolinesulfonic Acid Hemihydrate
CAS No.	306935-17-1
Molecular Formula	C9H7NO3S2 • ½H2O
Molecular Weight	246.29 g/mol (Anhydrous basis)
Synonyms	8-Mercapto-5-quinolinesulfonic Acid Hemihydrate; 5-Quinolinesulfonic Acid, 8-mercapto-, hemihydrate; 8-Thio-5-quinolinesulfonic Acid Hemihydrate; 8-SH-5-QSA; 8-Mercaptoquinoline-5-sulfonic Acid Hemihydrate
EINECS	Contact for details

Quality Control

Our 8-Sulfanyl-5-Quinolinesulfonic Acid Hemihydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, residual solvents, and water content (KF), ensuring it meets the stringent requirements for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its properties of being easily oxidized (store under inert atmosphere) and compatibility with strong acid/organic solvent, it should be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and separated from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	3.0 - 5.0% (Theoretical for hemihydrate ~3.66%)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.