Description

5-Nitrospiro[Benzimidazole-2,1'-Cyclohexan]-4-Amine 1-Oxide is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic benzimidazole structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic frameworks. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, agrochemicals, and specialized organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of new drug molecules, especially those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or pesticides that leverage the benzimidazole core for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex spirocyclic and fused heterocyclic compounds.
• Biochemical Probe Development: Serves as a starting material for creating molecular probes used in biochemical assays and diagnostic research.
• Material Science Research: Investigated for potential applications in creating organic electronic materials or specialty polymers.

Basic Information

Product Name	5-Nitrospiro[Benzimidazole-2,1'-Cyclohexan]-4-Amine 1-Oxide
CAS No.	306934-81-6
Molecular Formula	C₁₃H₁₄N₄O₃
Molecular Weight	274.28 g/mol
Synonyms	5-Nitrospiro[benzimidazole-2,1'-cyclohexan]-4-amine 1-oxide; 5-Nitro-1-oxo-1,4-dihydrospiro[benzimidazole-2,1'-cyclohexane]-4-amine; 4-Amino-5-nitrospiro[benzimidazole-2,1'-cyclohexane] 1-oxide; Spiro[cyclohexane-1,2'-benzimidazole]-4-amine, 5-nitro-, 1'-oxide; 306934-81-6; 5-Nitro-spiro[benzimidazole-2,1'-cyclohexane]-4-amine 1-oxide
EINECS	Contact for details

Quality Control

Our 5-Nitrospiro[Benzimidazole-2,1'-Cyclohexan]-4-Amine 1-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.