Description

Oxiranebutanol, 3-Ethynyl-, (2R,3R)-Rel- (9Ci) is a high-purity, chiral epoxide building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both an epoxide ring and a terminal alkyne functional group, makes it a versatile precursor for constructing complex, stereodefined molecular scaffolds. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of complex drug molecules and bioactive compounds.
• Organic Synthesis Building Block: Used in click chemistry (e.g., copper-catalyzed azide-alkyne cycloaddition) and ring-opening reactions to introduce functionalized fragments.
• Agrochemical Research: Serves as a precursor in the development of novel, stereospecific pesticides and herbicides.
• Material Science: Employed in the synthesis of specialized polymers, dendrimers, and advanced materials with tailored properties.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules due to its reactive alkyne and epoxide handles.
• Catalyst and Ligand Development: Acts as a starting material for creating chiral ligands and organocatalysts.

Basic Information

Product Name	Oxiranebutanol, 3-Ethynyl-, (2R,3R)-Rel- (9Ci)
CAS No.	306734-30-5
Molecular Formula	C6H8O2
Molecular Weight	112.13 g/mol
Synonyms	(2R,3R)-3-Ethynyloxiran-2-ylmethanol; (2R,3R)-3-Ethynyl-2-oxiranemethanol; rel-(2R,3R)-3-Ethynyloxiran-2-ylmethanol; 3-Ethynyloxirane-2-methanol, (2R,3R)-rel-; Glycidol derivative, 3-ethynyl-; Chiral glycidol alkyne; (R,R)-3-Ethynylglycidol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Oxiranebutanol, 3-Ethynyl-, (2R,3R)-Rel- (9Ci) is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy to confirm identity, enantiomeric excess, and purity. Certificates of Analysis (COA) with detailed specifications are available upon request. We adhere to cGMP principles for the manufacture of advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.