Description

1,4-Dihydro-6-Nitro-4-Oxo-1,8-Naphthyridine-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its naphthyridine core structure. This compound is valued for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic agents and specialty chemicals. Our supply is backed by stringent quality control to ensure batch-to-batch consistency for your sensitive synthesis processes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of quinolone and naphthyridine-based antibiotic APIs.
• Agrochemical Research: Serves as a key scaffold for developing new herbicides and pesticides with specific modes of action.
• Chemical Synthesis: Used as a versatile building block for constructing complex heterocyclic compounds in medicinal chemistry.
• Biochemical Research: Employed in studies targeting bacterial DNA gyrase and topoisomerase IV enzymes.
• Material Science: Investigated for the development of organic electronic materials and fluorescent dyes.

Basic Information

Product Name	1,4-Dihydro-6-Nitro-4-Oxo-1,8-Naphthyridine-3-Carbonitrile
CAS No.	305370-83-6
Molecular Formula	C9H4N4O3
Molecular Weight	216.16 g/mol
Synonyms	6-Nitro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carbonitrile; 3-Cyano-6-nitro-1,4-dihydro-1,8-naphthyridin-4-one; 6-Nitro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbonitrile; 1,8-Naphthyridine-3-carbonitrile, 1,4-dihydro-6-nitro-4-oxo-; 305370-83-6; 6-Nitro-1,8-naphthyridone-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 1,4-Dihydro-6-Nitro-4-Oxo-1,8-Naphthyridine-3-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and conformity to agreed specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.