Description

4-(([5-(Methylsulfanyl)-1H-1,2,4-Triazol-3-Yl]Amino)Methyl)-1(2H)-Phthalazinone is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining phthalazinone and triazole moieties. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Biochemical Probe Development: Serves as a core scaffold for creating chemical probes to study specific enzyme functions and biological pathways.
• Fine Chemical Synthesis: Intermediate for the production of complex, high-value specialty chemicals with biological activity.
• Academic & Contract Research: Utilized in university and CRO settings for exploratory research into new heterocyclic compounds.

Basic Information

Product Name	4-(([5-(Methylsulfanyl)-1H-1,2,4-Triazol-3-Yl]Amino)Methyl)-1(2H)-Phthalazinone
CAS No.	305368-16-5
Molecular Formula	C12H12N6OS
Molecular Weight	288.33 g/mol
Synonyms	4-[(5-Methylsulfanyl-1H-1,2,4-triazol-3-ylamino)methyl]-1(2H)-phthalazinone; 4-[[(5-Methylthio-1H-1,2,4-triazol-3-yl)amino]methyl]-1(2H)-phthalazinone; 1(2H)-Phthalazinone, 4-[[(5-(methylthio)-1H-1,2,4-triazol-3-yl)amino]methyl]-; 305368-16-5; 4-((5-(Methylthio)-1H-1,2,4-triazol-3-ylamino)methyl)phthalazin-1(2H)-one
EINECS	Contact for details

Quality Control

Our 4-(([5-(Methylsulfanyl)-1H-1,2,4-Triazol-3-Yl]Amino)Methyl)-1(2H)-Phthalazinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.