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7-Amino-1-Methyl-1,2,3,4-Tetrahydroquinoline CAS NO 304690-94-6
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CAS No.:304690-94-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
7-Amino-1-Methyl-1,2,3,4-Tetrahydroquinoline is a versatile, nitrogen-containing heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its value lies in its fused quinoline-tetrahydroquinoline structure, which provides a privileged scaffold for developing molecules with targeted biological and functional properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its structural similarity to bioactive alkaloids.
- Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where its heterocyclic core contributes to binding affinity and efficacy.
- Organic Light-Emitting Diode (OLED) Materials: Serves as a starting material for electron-transporting or host materials in OLED displays and lighting, leveraging its electron-donating amino group and rigid structure.
- Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized quinoline-based dyes, pigments, and fluorescent markers.
- Catalyst Ligand Precursor: Utilized in the preparation of nitrogen-donor ligands for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.
- Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
Basic Information
| Product Name | 7-Amino-1-Methyl-1,2,3,4-Tetrahydroquinoline |
| CAS No. | 304690-94-6 |
| Molecular Formula | C10H14N2 |
| Molecular Weight | 162.23 g/mol |
| Synonyms | 1-Methyl-1,2,3,4-tetrahydroquinolin-7-amine; 1-Methyl-7-amino-1,2,3,4-tetrahydroquinoline; 7-Amino-1-methyl-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-1-methyl-7-quinolinamine; 1-Methyl-1,2,3,4-tetrahydro-7-quinolinamine; 7-Amino-1-methyl-THQ |
| EINECS | Contact for details |
Quality Control
Our 7-Amino-1-Methyl-1,2,3,4-Tetrahydroquinoline is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals (as Pb) | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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