Description

3,4-Dihydro-2H-Quinolin-1-Ylamine Hydrochloride is a high-purity organic salt and a valuable synthetic intermediate in advanced chemical synthesis. Its significance lies in its role as a versatile building block for constructing complex nitrogen-containing heterocycles, which are core structures in numerous active pharmaceutical ingredients. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, particularly for central nervous system (CNS) and anti-infective applications.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging the biological activity of the quinoline scaffold.
• Fine Chemical Building Block: Employed in custom synthesis and research to create complex molecules for material science and specialty chemicals.
• Academic & Contract Research: Serves as a critical reagent in medicinal chemistry research programs within universities and contract research organizations (CROs).
• Chemical Library Development: Utilized for the generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	3,4-Dihydro-2H-Quinolin-1-Ylamine Hydrochloride
CAS No.	303801-64-1
Molecular Formula	C9H12N2·HCl
Molecular Weight	184.66 g/mol
Synonyms	1-Amino-1,2,3,4-tetrahydroquinoline hydrochloride; 1,2,3,4-Tetrahydroquinolin-1-amine hydrochloride; 1-Aminotetrahydroquinoline HCl; Quinolin-1-amine, 1,2,3,4-tetrahydro-, hydrochloride; 3,4-Dihydro-2H-quinolin-1-ylamine hydrochloride; 1-Amino-3,4-dihydro-2H-quinoline hydrochloride
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-2H-Quinolin-1-Ylamine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.