Description

4-Chloro-2-(Chloromethyl)-Quinoline is a versatile and highly functionalized quinoline derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a chloro and a chloromethyl substituent, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the quinoline scaffold provides biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology: Employed as a molecular probe or a linker in bioconjugation chemistry due to its reactive chloromethyl group.
• Fine Chemical Production: Intermediate for the manufacture of dyes, pigments, and other complex specialty chemicals.

Basic Information

Product Name	4-Chloro-2-(Chloromethyl)-Quinoline
CAS No.	303224-88-6
Molecular Formula	C10H7Cl2N
Molecular Weight	212.08 g/mol
Synonyms	2-(Chloromethyl)-4-chloroquinoline; 4-Chloro-2-chloromethylquinoline; Quinoline, 4-chloro-2-(chloromethyl)-; 4-Chloro-2-(chloromethyl)quinoline; 2-Chloromethyl-4-chloroquinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Chloromethyl)-Quinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.