Description

2-(4-Methoxyphenyl)-4,4,8-Trimethyl-4,5-Dihydro[1,2]Thiazolo[5,4-C]Quinoline-1(2H)-Thione is a high-purity, complex heterocyclic organic compound featuring a fused thiazoloquinoline core structure. This specialized chemical is valued for its unique molecular architecture, which makes it a critical advanced intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents and high-performance organic compounds.

Application

This compound serves as a sophisticated building block in advanced chemical synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or oncology.
• Organic Light-Emitting Diode (OLED) Materials Research: Used in the development of novel electron-transport or host materials due to its fused heterocyclic, electron-deficient structure.
• Agrochemical Synthesis: Acts as an intermediate for creating new generations of herbicides, fungicides, or insecticides with enhanced efficacy and selectivity.
• Ligand Synthesis for Catalysis: The thione and nitrogen-containing heterocycles can be utilized to synthesize novel ligands for transition metal catalysts used in cross-coupling and other organic transformations.
• Dye and Pigment Chemistry: Serves as a core structure for developing new classes of functional dyes, pigments, or photographic sensitizers.
• Academic and Industrial Research: A valuable compound for studying structure-activity relationships (SAR), photophysical properties, and novel heterocyclic reaction chemistry.

Basic Information

Product Name	2-(4-Methoxyphenyl)-4,4,8-Trimethyl-4,5-Dihydro[1,2]Thiazolo[5,4-C]Quinoline-1(2H)-Thione
CAS No.	303177-20-0
Molecular Formula	C20H20N2OS2
Molecular Weight	368.52 g/mol
Synonyms	4,5-Dihydro-2-(4-methoxyphenyl)-4,4,8-trimethyl[1,2]thiazolo[5,4-c]quinoline-1(2H)-thione; [1,2]Thiazolo[5,4-c]quinoline-1(2H)-thione, 4,5-dihydro-2-(4-methoxyphenyl)-4,4,8-trimethyl-; 2-(4-Methoxyphenyl)-4,4,8-trimethyl-4,5-dihydro[1,2]thiazolo[5,4-c]quinoline-1-thione; Thiazoloquinoline thione derivative; CAS 303177-20-0
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this advanced intermediate. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and every batch is analyzed using advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.