Description

1,8-Naphthyridine,7-(1H-1,2,4-Triazol-3-Ylthio)-2,4-Bis(Trifluoromethyl)-(9Ci) is a high-value, multi-functional heterocyclic compound that serves as a critical advanced pharmaceutical intermediate and organic synthesis building block. Its unique molecular architecture, featuring a naphthyridine core modified with a triazole-thioether and trifluoromethyl groups, makes it indispensable for developing novel active ingredients. This compound is primarily sought by pharmaceutical R&D and agrochemical sectors for creating next-generation therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-infective research.
• Agrochemical Synthesis: Used in the development of advanced fungicides, herbicides, and pesticides with enhanced efficacy and selectivity.
• Chemical Biology Probe: Serves as a scaffold or ligand in the design of molecular probes for studying enzyme inhibition and biological pathways.
• Material Science Research: Investigated as a precursor for functional materials, including ligands for metal-organic frameworks (MOFs) or catalysts.
• Organic Light-Emitting Diode (OLED) Materials: Potential use in the development of electron-transport or host materials due to its rigid, conjugated structure.
• Academic & Contract Research: Supplied to universities and CROs for fundamental research in medicinal and synthetic organic chemistry.

Basic Information

Product Name	1,8-Naphthyridine,7-(1H-1,2,4-Triazol-3-Ylthio)-2,4-Bis(Trifluoromethyl)-(9Ci)
CAS No.	303151-91-9
Molecular Formula	C₁₃H₅F₆N₅S
Molecular Weight	385.27 g/mol
Synonyms	7-[(1H-1,2,4-Triazol-3-yl)thio]-2,4-bis(trifluoromethyl)-1,8-naphthyridine; 2,4-Bis(trifluoromethyl)-7-[(1H-1,2,4-triazol-3-yl)thio]-1,8-naphthyridine; 7-(1H-1,2,4-Triazol-3-ylthio)-2,4-bis(trifluoromethyl)-1,8-naphthyridine; 303151-91-9; 1,8-Naphthyridine, 7-[(1H-1,2,4-triazol-3-yl)thio]-2,4-bis(trifluoromethyl)-; 7-(1,2,4-Triazol-3-ylthio)-2,4-bis(trifluoromethyl)-1,8-naphthyridine
EINECS	Contact for details

Quality Control

Our production of 1,8-Naphthyridine,7-(1H-1,2,4-Triazol-3-Ylthio)-2,4-Bis(Trifluoromethyl)-(9Ci) adheres to stringent GMP-like guidelines to ensure batch-to-batch consistency and high purity for research and development applications. Every lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture and contamination. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.