Description

3-(3-Nitrophenyl)-5-(Trifluoromethyl)[1,2,4]Triazolo[4,3-C]Quinazoline CAS NO 303149-04-4 is a high-value, heterocyclic organic compound featuring a fused triazoloquinazoline core substituted with a nitrophenyl and a trifluoromethyl group. This unique molecular architecture makes it a critical advanced intermediate for research and development in pharmaceutical and agrochemical discovery. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in kinase inhibitor programs and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially for targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic structure.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme inhibition and biological pathways.
• Material Science Precursor: Investigated for creating specialty chemicals with unique electronic or photophysical properties.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and the production of non-commercial quantities for clinical trials.

Basic Information

Product Name	3-(3-Nitrophenyl)-5-(Trifluoromethyl)[1,2,4]Triazolo[4,3-C]Quinazoline
CAS No.	303149-04-4
Molecular Formula	C₁₇H₈F₃N₅O₂
Molecular Weight	371.27 g/mol
Synonyms	3-(3-Nitrophenyl)-5-(trifluoromethyl)-[1,2,4]triazolo[4,3-c]quinazoline; 5-(Trifluoromethyl)-3-(3-nitrophenyl)-[1,2,4]triazolo[4,3-c]quinazoline; [1,2,4]Triazolo[4,3-c]quinazoline, 3-(3-nitrophenyl)-5-(trifluoromethyl)-; 303149-04-4; 3-(3-Nitrophenyl)-5-(trifluoromethyl)-1,2,4-triazolo[4,3-c]quinazoline; 5-Trifluoromethyl-3-(3-nitrophenyl)-[1,2,4]triazolo[4,3-c]quinazoline
EINECS	Contact for details

Quality Control

Our 3-(3-Nitrophenyl)-5-(Trifluoromethyl)[1,2,4]Triazolo[4,3-C]Quinazoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and MS. Our quality commitment supports compliance with cGMP standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.