Description

Methyl 2-[1-(3-Hydroxyphenyl)Ethylidene]-1-Hydrazinecarboxylate CAS NO 303148-72-3 is a specialized organic compound featuring a hydrazinecarboxylate core linked to a 3-hydroxyphenyl moiety. This structure makes it a valuable key intermediate and building block in advanced synthetic chemistry, particularly for constructing complex heterocyclic systems. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides and plant growth regulators, leveraging its bioactive hydrazone structure.
• Dye and Pigment Manufacturing: Serves as a building block for creating specialized azo dyes and colorants with enhanced lightfastness.
• Ligand and Chelating Agent Precursor: The phenolic hydroxyl and hydrazide groups make it suitable for synthesizing complexing agents used in catalysis and metal ion sequestration.
• Polymer Additive Research: Investigated for use in creating specialty polymers with specific thermal or UV-stabilizing properties.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in organic synthesis and heterocycle formation.

Basic Information

Product Name	Methyl 2-[1-(3-Hydroxyphenyl)Ethylidene]-1-Hydrazinecarboxylate
CAS No.	303148-72-3
Molecular Formula	C11H12N2O3
Molecular Weight	220.23 g/mol
Synonyms	Methyl (1E)-2-[1-(3-hydroxyphenyl)ethylidene]hydrazinecarboxylate; 1-Hydrazinecarboxylic acid, 2-[1-(3-hydroxyphenyl)ethylidene]-, methyl ester; Methyl 2-(1-(3-hydroxyphenyl)ethylidene)hydrazine-1-carboxylate; 3-Hydroxyacetophenone methylcarbazate; (E)-Methyl 2-(1-(3-hydroxyphenyl)ethylidene)hydrazinecarboxylate; Acetophenone, 3-hydroxy-, methylcarbazone; Methyl carbazate of 3-hydroxyacetophenone
EINECS	Contact for details

Quality Control

Our Methyl 2-[1-(3-Hydroxyphenyl)Ethylidene]-1-Hydrazinecarboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ISO guidelines for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive and hygroscopic; keep the container tightly sealed under an inert atmosphere if specified for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.