Description

4-[6-[(Phenylsulfonyl)Methyl]-2-(2-Pyridinyl)-4-Pyrimidinyl]Morpholine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for specialized medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs within academic and industrial R&D labs.
• Biochemical Tool Compound: May be employed as a reference standard or probe in biochemical assays to study specific biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Process Chemistry Development: Used to develop and scale up efficient, GMP-compliant synthetic routes for new chemical entities (NCEs).

Basic Information

Product Name	4-[6-[(Phenylsulfonyl)Methyl]-2-(2-Pyridinyl)-4-Pyrimidinyl]Morpholine
CAS No.	303147-55-9
Molecular Formula	C20H20N4O3S
Molecular Weight	396.46 g/mol
Synonyms	4-[6-(Phenylsulfonylmethyl)-2-pyridin-2-ylpyrimidin-4-yl]morpholine; 4-(6-((Phenylsulfonyl)methyl)-2-(pyridin-2-yl)pyrimidin-4-yl)morpholine; Morpholine, 4-[6-[(phenylsulfonyl)methyl]-2-(2-pyridinyl)-4-pyrimidinyl]-; 303147-55-9; UNII-6G6O5P8K8H; 6G6O5P8K8H; BDBM50111679; AKOS025310584; ZINC000004143768
EINECS	Contact for details

Quality Control

Our 4-[6-[(Phenylsulfonyl)Methyl]-2-(2-Pyridinyl)-4-Pyrimidinyl]Morpholine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and cGMP-grade requirements, with specifications tailored to your project phase.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.