Description

Neocuproine Hydrochloride Hydrate 98 is a high-purity, water-soluble derivative of the classic copper(I)-specific chelator, 2,9-dimethyl-1,10-phenanthroline. This compound is essential for analytical and biochemical research where precise quantification and sequestration of cuprous ions (Cu+) are required. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, environmental, and life science sectors for applications ranging from antioxidant capacity assays to enzymatic studies.

Application

• CUPRAC Antioxidant Capacity Assay: Serves as the primary chromogenic reagent for the spectrophotometric determination of total antioxidant activity in biological fluids, food products, and plant extracts.
• Biochemical Research: Used as a selective chelating agent to inhibit copper-containing enzymes (e.g., superoxide dismutase, tyrosinase) or to study copper-dependent biological pathways.
• Analytical Chemistry: Employed in the development of colorimetric and fluorometric sensors for the detection of reducing agents, sugars, and specific metal ions.
• Pharmaceutical Analysis: Applied in methods for assessing the antioxidant properties of drug candidates and natural products.
• Material Science: Can be used in the synthesis of copper(I) complexes for catalytic or photoluminescent applications.

Basic Information

Product Name	Neocuproine Hydrochloride Hydrate 98
CAS No.	303136-82-5
Molecular Formula	C14H12N2·HCl·xH2O
Molecular Weight	Anhydrous Free Base: 208.26 g/mol
Synonyms	2,9-Dimethyl-1,10-phenanthroline hydrochloride hydrate; Neocuproine HCl hydrate; Cuprous ion specific indicator; Bathocuproinedisulfonic acid disodium salt related chelator; CUPRAC reagent; Neocuproin hydrochloride; 2,9-Dimethyl-4,7-diphenyl-1,10-phenanthroline (common name variant).
EINECS	Contact for details

Quality Control

Our Neocuproine Hydrochloride Hydrate 98 is manufactured under strict quality protocols. Each batch is tested to ensure it meets the high-purity standards required for sensitive analytical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substance tests is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which may affect performance.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Solubility	Clear, orange solution in water or methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.