Description

Methyl 2-(4-Aminothian-4-Yl)Acetate Hydrochloride is a high-purity organic salt, primarily utilized as a critical pharmaceutical intermediate in the synthesis of complex active pharmaceutical ingredients (APIs). Its value lies in its role as a versatile building block, enabling the introduction of specific functional groups essential for biological activity. This compound is particularly relevant for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors seeking reliable, high-quality intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its unique heterocyclic structure.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, dyes, and complex organic molecules in research laboratories.
• Bioconjugation & Linker Chemistry: The amine and ester functional groups make it suitable for creating peptide mimetics or as a linker in prodrug design.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	Methyl 2-(4-Aminothian-4-Yl)Acetate Hydrochloride
CAS No.	303037-43-6
Molecular Formula	C8H16ClNO2S
Molecular Weight	225.73 g/mol
Synonyms	Methyl (4-Aminothian-4-yl)acetate hydrochloride; 4-Aminothiane-4-acetic acid methyl ester hydrochloride; 2-(4-Aminothian-4-yl)acetic acid methyl ester hydrochloride; Thiane-4-acetic acid, 4-amino-, methyl ester, hydrochloride; Methyl 4-aminothiane-4-carboxylate hydrochloride (common misnomer); 303037-43-6; 4-Aminothiane-4-yl-acetic acid methyl ester HCl
EINECS	Contact for details

Quality Control

Our Methyl 2-(4-Aminothian-4-Yl)Acetate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.