Description

7-Chloro-8-Methyl-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid is a high-purity, synthetically derived quinoline derivative that serves as a critical advanced pharmaceutical intermediate. This compound matters because it provides a structurally defined and reliable building block for the research and development of novel active pharmaceutical ingredients (APIs), particularly in the antimicrobial and anti-inflammatory therapeutic classes. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) engaged in the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinolone and fluoroquinolone antibiotic candidates.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry programs targeting various biological pathways.
• Fine Chemical Synthesis: Used in the multi-step production of complex, high-value specialty chemicals for agrochemical and material science applications.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry, reaction mechanisms, and structure-activity relationships (SAR).

Basic Information

Product Name	7-Chloro-8-Methyl-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid
CAS No.	302949-00-4
Molecular Formula	C12H8ClNO3
Molecular Weight	249.65 g/mol
Synonyms	7-Chloro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 7-chloro-1,4-dihydro-8-methyl-4-oxo-; 7-Chloro-8-methyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 7-Chloro-8-methyl-4-oxo-1H-quinoline-3-carboxylic acid; 302949-00-4; 7-Chloro-8-methyl-4-oxoquinoline-3-carboxylic acid; 1,4-Dihydro-7-chloro-8-methyl-4-oxo-3-quinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Chloro-8-Methyl-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is compatible with strong acids and organic solvents but should be kept separate from strong bases and oxidizing agents. Keep the container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.