Description

6-Amino-3-Methyl-4-(2,4,5-Trimethoxyphenyl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyranopyrazole chemical class. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in modern medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting a range of therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses due to its reactive amino and nitrile functional groups.
• Chemical Biology Probes: Serves as a starting material for developing specialized molecular probes to study biological pathways.
• Process Chemistry Development: Used in scaling up and optimizing synthetic routes for potential active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Utilized in universities and research institutes for exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	6-Amino-3-Methyl-4-(2,4,5-Trimethoxyphenyl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	302788-93-8
Molecular Formula	C₁₇H₁₈N₄O₄
Molecular Weight	342.35 g/mol
Synonyms	6-Amino-3-methyl-4-(2,4,5-trimethoxyphenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 1,4-Dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-3-methyl-4-(2,4,5-trimethoxyphenyl)-; 302788-93-8; 4-(2,4,5-Trimethoxyphenyl)-6-amino-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; Pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-1,4-dihydro-3-methyl-4-(2,4,5-trimethoxyphenyl)-; Fused Pyranopyrazole Derivative; Advanced Pharmaceutical Intermediate (API Intermediate)
EINECS	Contact for details

Quality Control

Our 6-Amino-3-Methyl-4-(2,4,5-Trimethoxyphenyl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.