Description

2-Azaspiro[4.4]Non-1-Ene,6,6-Dimethyl-,(5R)-(9Ci) is a chiral, nitrogen-containing spirocyclic building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional structure makes it a valuable scaffold for constructing complex molecules with defined stereochemistry. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its spirocyclic framework can contribute to unique biological activity and stability.
• Ligand and Catalyst Development: Employed as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme function and protein-protein interactions due to its structural complexity.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.

Basic Information

Product Name	2-Azaspiro[4.4]Non-1-Ene,6,6-Dimethyl-,(5R)-(9Ci)
CAS No.	302338-16-5
Molecular Formula	C10H17N
Molecular Weight	151.25 g/mol
Synonyms	(5R)-6,6-Dimethyl-2-azaspiro[4.4]non-1-ene; (5R)-6,6-Dimethyl-2-azaspiro[4.4]non-1-ene (9CI); 2-Azaspiro[4.4]non-1-ene, 6,6-dimethyl-, (5R)-; (R)-6,6-Dimethyl-2-azaspiro[4.4]non-1-ene; 302338-16-5; SCHEMBL21806227; DTXSID60674488
EINECS	Contact for details

Quality Control

Every batch of 2-Azaspiro[4.4]Non-1-Ene,6,6-Dimethyl-,(5R)-(9Ci) is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet the exacting standards required for research and process development. A detailed Certificate of Analysis (COA) including results from chiral HPLC, NMR, and GC/MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.