Description

2,3-Dihydrobenzofuran-6-Carboxylic Acid is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its fused benzofuran-carboxylic acid structure makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a precursor for functional polymers, liquid crystals, and organic electronic materials due to its rigid, planar structure.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including catalysis, cross-coupling reactions, and heterocycle functionalization.

Basic Information

Product Name	2,3-Dihydrobenzofuran-6-Carboxylic Acid
CAS No.	301836-57-7
Molecular Formula	C9H8O3
Molecular Weight	164.16 g/mol
Synonyms	6-Carboxy-2,3-dihydrobenzofuran; 2,3-Dihydro-6-benzofurancarboxylic Acid; 2,3-Dihydrobenzofuran-6-carboxylic acid; 6-(Carboxy)-2,3-dihydrobenzofuran; 2,3-Dihydro-1-benzofuran-6-carboxylic acid; Dihydrobenzofuran-6-carboxylic acid; 6-Carboxy-2,3-dihydro-1-benzofuran
EINECS	Contact for details

Quality Control

Our 2,3-Dihydrobenzofuran-6-Carboxylic Acid is manufactured under a strict quality management system. We provide material suitable for research and development purposes, with typical purity levels exceeding 95% (HPLC). Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch. Specifications can be developed to meet the requirements of cGMP, ICH Q7, or other relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.