Description

2-(Benzylsulfanyl)-3-Phenyl-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclopentan]-4(6H)-One is a complex spirocyclic quinazoline derivative, a high-value synthetic intermediate prized for its unique molecular architecture. This compound matters for its role as a key building block in advanced organic synthesis, particularly in the development of novel pharmacologically active molecules. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its spirocyclic structure for enhanced biological activity and stability.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a potential electron-transport or host material in the research of next-generation OLED displays and lighting due to its rigid, conjugated structure.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies in spiroannulation and heterocyclic chemistry.
• Chemical Library Synthesis: A valuable scaffold for creating diverse compound libraries used in high-throughput screening (HTS) for drug discovery.
• Material Science Prototyping: Investigated for its potential application in creating organic semiconductors or non-linear optical (NLO) materials.

Basic Information

Product Name	2-(Benzylsulfanyl)-3-Phenyl-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclopentan]-4(6H)-One
CAS No.	301352-35-2
Molecular Formula	C30H24N2OS
Molecular Weight	460.59 g/mol
Synonyms	2-(Benzylthio)-3-phenyl-3H-spiro[benzo[h]quinazoline-5,1'-cyclopentan]-4(6H)-one; 3H-Spiro[benzo[h]quinazoline-5,1'-cyclopentan]-4(6H)-one, 2-(benzylthio)-3-phenyl-; 2-(Phenylmethylthio)-3-phenyl-3H-spiro[benzo[h]quinazoline-5,1'-cyclopentan]-4(6H)-one; Benzyl 3-phenyl-4-oxo-3,4,5,6-tetrahydrospiro[benzo[h]quinazoline-5,1'-cyclopentane]-2-yl sulfide; CAS 301352-35-2
EINECS	Contact for details

Quality Control

Our 2-(Benzylsulfanyl)-3-Phenyl-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclopentan]-4(6H)-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO 9001 compliant manufacturing for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability. Keep the container sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.