Description

4-(3-Oxo-4-Phenyl-Butyryl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold and a protected carboxylic acid group. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring complex heterocyclic structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of protease inhibitors due to its specific molecular architecture.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Chemical Library Development: Used to create diverse compound libraries for high-throughput screening in drug discovery.
• Academic Research: Utilized in university and institutional labs for studying organic reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	4-(3-Oxo-4-Phenyl-Butyryl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	301219-11-4
Molecular Formula	C20H27NO4
Molecular Weight	345.44 g/mol
Synonyms	1-Boc-4-(3-oxo-4-phenylbutyryl)piperidine; tert-Butyl 4-(3-oxo-4-phenylbutanoyl)piperidine-1-carboxylate; 4-(3-Oxo-4-phenylbutyryl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(3-oxo-4-phenylbutyryl)piperidine; Piperidine-1-carboxylic acid, 4-(3-oxo-4-phenylbutanoyl)-, 1,1-dimethylethyl ester; BOC-4-(3-Oxo-4-phenylbutyryl)piperidine; 301219-11-4
EINECS	Contact for details

Quality Control

Our 4-(3-Oxo-4-Phenyl-Butyryl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediates, ensuring traceability and documentation integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.