Description

4-[4-(tert-Butyl)Phenyl]-4-Oxo-2-(1-Pyrrolidinyl)Butanoic Acid is a high-purity, non-natural amino acid derivative characterized by its unique tert-butylphenyl and pyrrolidinyl substituents. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting neurological or metabolic pathways.
• Peptidomimetic Research: Used to incorporate non-natural amino acid motifs into peptide analogs to enhance stability, bioavailability, or receptor binding affinity.
• Chemical Biology Probes: Serves as a building block for creating specialized probes and inhibitors to study enzyme function and protein-protein interactions.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced, high-performance crop protection agents.
• Material Science: Can be utilized in the development of specialty polymers and advanced organic materials with tailored properties.

Basic Information

Product Name	4-[4-(tert-Butyl)Phenyl]-4-Oxo-2-(1-Pyrrolidinyl)Butanoic Acid
CAS No.	301193-77-1
Molecular Formula	C18H25NO3
Molecular Weight	303.40 g/mol
Synonyms	2-(Pyrrolidin-1-yl)-4-[4-(tert-butyl)phenyl]-4-oxobutanoic acid; 4-Oxo-4-[4-(1,1-dimethylethyl)phenyl]-2-(1-pyrrolidinyl)butanoic acid; 4-(4-tert-Butylphenyl)-4-oxo-2-(pyrrolidin-1-yl)butanoic acid; 301193-77-1; Butanoic acid, 4-[4-(1,1-dimethylethyl)phenyl]-4-oxo-2-(1-pyrrolidinyl)-; 4-(4-tert-butylphenyl)-2-(pyrrolidin-1-yl)-4-oxobutanoic acid
EINECS	Contact for details

Quality Control

Our 4-[4-(tert-Butyl)Phenyl]-4-Oxo-2-(1-Pyrrolidinyl)Butanoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.