Description

8-Methyl-2,4-Dichloroquinazoline is a versatile halogenated quinazoline derivative, a key heterocyclic building block in advanced organic synthesis. Its value lies in its dual reactive chlorine sites, which allow for selective functionalization to create complex molecular architectures. This intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various quinazoline-based drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, leveraging the bioactive quinazoline core.
• Material Science Research: Serves as a building block for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specific, multi-functionalized quinazoline structures.

Basic Information

Product Name	8-Methyl-2,4-Dichloroquinazoline
CAS No.	39576-83-5
Molecular Formula	C9H6Cl2N2
Molecular Weight	213.06 g/mol
Synonyms	2,4-Dichloro-8-methylquinazoline; 8-Methyl-2,4-dichloroquinazoline; Quinazoline, 2,4-dichloro-8-methyl-; 39576-83-5; 2,4-Dichloro-8-methyl-quinazoline; 8-Methylquinazoline-2,4-dichloride
EINECS	Contact for details

Quality Control

Our 8-Methyl-2,4-Dichloroquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.