Description

1-(Chloromethyl)-3,5-Bis(Methylsulfonyl)Benzene is a high-value, multi-functional aromatic building block characterized by its reactive chloromethyl and electron-withdrawing methylsulfonyl groups. This compound matters for its versatility as a key intermediate in the synthesis of complex molecules, enabling the introduction of specific functional handles for further chemical elaboration. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a disubstituted benzene core with specific electronic properties.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where its structural motifs contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organocatalysis.
• Polymer and Material Science: Employed in the production of specialty polymers, resins, and advanced organic materials with tailored thermal or electronic characteristics.
• Chemical Research & Development: A valuable reagent for exploring novel organic reactions and constructing complex molecular architectures in academic and industrial labs.
• Cross-Coupling Reactions: The chloromethyl group acts as a versatile handle for further functionalization via various palladium-catalyzed or nucleophilic substitution reactions.

Basic Information

Product Name	1-(Chloromethyl)-3,5-Bis(Methylsulfonyl)Benzene
CAS No.	39552-81-3
Molecular Formula	C9H11ClO4S2
Molecular Weight	282.76 g/mol
Synonyms	3,5-Bis(methylsulfonyl)benzyl chloride; Benzene, 1-(chloromethyl)-3,5-bis(methylsulfonyl)-; α-Chloro-3,5-bis(methylsulfonyl)toluene; (3,5-Bis(methylsulfonyl)phenyl)methyl chloride; 3,5-Dimethylsulfonylbenzyl chloride
EINECS	Contact for details

Quality Control

Our 1-(Chloromethyl)-3,5-Bis(Methylsulfonyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.