Description

4-Chloro-3-Nitro-8-(Trifluoromethyl)Quinoline is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring a halogen, nitro, and trifluoromethyl group on a quinoline scaffold, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for developing new antimicrobial, anticancer, or anti-inflammatory agents.
• Agrochemical Research: Serves as a critical building block for creating novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science: Used in the development of advanced organic electronic materials, such as OLEDs or charge-transport layers, due to its electron-deficient quinoline structure.
• Dye & Pigment Synthesis: Acts as an intermediate for producing specialized quinoline-based dyes and pigments with specific color and stability properties.
• Ligand & Catalyst Development: Employed in the creation of novel chelating ligands or organocatalysts for asymmetric synthesis and metal complexation.

Basic Information

Product Name	4-Chloro-3-Nitro-8-(Trifluoromethyl)Quinoline
CAS No.	39487-89-3
Molecular Formula	C10H4ClF3N2O2
Molecular Weight	276.60 g/mol
Synonyms	8-(Trifluoromethyl)-4-chloro-3-nitroquinoline; 4-Chloro-3-nitro-8-(trifluoromethyl)quinoline; Quinoline, 4-chloro-3-nitro-8-(trifluoromethyl)-; 39487-89-3; 4-Chloro-3-nitro-8-trifluoromethylquinoline; 3-Nitro-4-chloro-8-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Nitro-8-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.