Description

6-Methoxy-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine Hydrochloride is a high-purity organic salt of a tetralin-based amine, serving as a critical advanced pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for the production of active pharmaceutical ingredients (APIs) and novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of central nervous system (CNS) active compounds and other therapeutic agents.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex tetralin and naphthalene derivatives.
• Academic & Contract Research: Utilized in university and CRO settings for methodological development and novel synthetic route exploration.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	6-Methoxy-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine Hydrochloride
CAS No.	39226-88-5
Molecular Formula	C11H16ClNO
Molecular Weight	213.70 g/mol
Synonyms	1-Amino-6-methoxy-1,2,3,4-tetrahydronaphthalene hydrochloride; 6-Methoxy-1,2,3,4-tetrahydro-1-naphthylamine hydrochloride; 6-Methoxy-1-tetralinamine hydrochloride; 1-(6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)amine hydrochloride; 6-Methoxy-1-amino-1,2,3,4-tetrahydronaphthalene HCl
EINECS	Contact for details

Quality Control

Our 6-Methoxy-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.