Description

Ethylenediaminetetraacetic Acid Calcium Disodium Salt Hydrate is a water-soluble, stable chelating agent widely used to sequester di- and trivalent metal ions. This compound is particularly valued for its ability to bind calcium and other heavy metals without contributing to electrolyte imbalance, making it a critical component in formulations requiring safe and effective metal deactivation. It is essential for manufacturers and researchers in the pharmaceutical, food, and analytical chemistry industries seeking a reliable chelator for stabilization, purification, and diagnostic applications.

Application

• Pharmaceutical Formulations: Used as a stabilizing agent in injectable solutions, ophthalmic preparations, and topical products to chelate metal impurities that can catalyze degradation.
• Food Additive (Antioxidant Synergist): Employed as a sequestrant to control trace metal ions that cause oxidation and color/flavor deterioration in canned foods, dressings, and beverages.
• Clinical & Diagnostic Reagents: Serves as a key anticoagulant in blood collection tubes (e.g., Vacutainer®) and as a chelator in various in-vitro diagnostic test kits and buffer solutions.
• Industrial Water Treatment: Acts as a scale inhibitor and chelating agent in boiler and cooling water systems to prevent deposits caused by calcium and magnesium ions.
• Cosmetics & Personal Care: Incorporated into creams, lotions, and shampoos as a stabilizer to enhance shelf-life by binding metal contaminants.
• Analytical Chemistry: Utilized as a titrant in complexometric titrations and as a masking agent in spectroscopic analysis to eliminate interference from specific metal ions.
• Agriculture & Horticulture: Applied in micronutrient fertilizer formulations and plant tissue culture media to maintain the bioavailability of essential metal nutrients.
• Cleaning & Detergent Formulations: Enhances the effectiveness of cleaners and detergents by softening water through the sequestration of calcium and magnesium ions.

Basic Information

Product Name	Ethylenediaminetetraacetic Acid Calcium Disodium Salt Hydrate
CAS No.	39208-14-5
Molecular Formula	C10H12CaN2Na2O8·xH2O
Molecular Weight	374.27 g/mol (Anhydrous basis)
Synonyms	Calcium Disodium EDTA; Edetate Calcium Disodium; Calcium Disodium Edetate; Calcium Disodium Ethylenediaminetetraacetate; (Ethylenedinitrilo)tetraacetic Acid Calcium Disodium Salt; Sequestrene NA2Ca; Versene CA; Antallin; Sodium Calcium Edetate; Edathamil Calcium Disodium; EDTA-CaNa2
EINECS	254-449-0

Quality Control

Our Ethylenediaminetetraacetic Acid Calcium Disodium Salt Hydrate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards, including specifications for assay, heavy metals, and loss on drying. We can supply material compliant with relevant pharmacopeial monographs (e.g., USP, EP, BP) or food-grade standards (FCC) upon request. A Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent caking and maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder or granules
Identification (IR)	Conforms to standard
Assay (Anhydrous Basis)	97.0% - 102.0%
pH (5% Solution)	6.5 - 8.0
Loss on Drying	Contact for details
Heavy Metals (as Pb)	≤ 20 ppm
Water (Karl Fischer)	Contact for details
Arsenic (As)	≤ 3 ppm
Calcium Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.