Description

(Mannose)6-(n-Acetylglucosamine)2-Asparagine is a high-purity, defined glycan structure, specifically an N-glycan core pentasaccharide. This compound is essential as a critical reference standard and biochemical tool for advancing glycobiology research and biopharmaceutical development. It is primarily needed by research institutions, diagnostic kit manufacturers, and biopharmaceutical companies working on glycosylation analysis, vaccine development, and therapeutic protein characterization.

Application

• Glycobiology Research: Serves as a precise standard for studying N-linked glycosylation pathways, enzyme specificity (e.g., glycosyltransferases, glycosidases), and carbohydrate-protein interactions.
• Biopharmaceutical Development: Used as a calibration standard in analytical methods (HPLC, MS, CE) for characterizing the glycosylation profiles of monoclonal antibodies, recombinant proteins, and other biologics to ensure batch consistency and efficacy.
• Diagnostic Reagent Manufacturing: Employed in the production and calibration of diagnostic assays and kits that detect specific glycan biomarkers associated with diseases like cancer, congenital disorders of glycosylation (CDG), and autoimmune conditions.
• Enzyme Activity Assays: Acts as a defined substrate for screening and quantifying the activity of enzymes involved in glycan synthesis and processing.
• Vaccine Research: Utilized in the development of conjugate vaccines and the study of glycan antigens present on pathogens and cell surfaces.
• Quality Control Reference: Provides an absolute reference material for quality control laboratories to validate analytical procedures and ensure the accuracy of glycan mapping in complex samples.

Basic Information

Product Name	(Mannose)6-(n-Acetylglucosamine)2-Asparagine
CAS No.	39114-02-8
Molecular Formula	C62H103N5O51
Molecular Weight	1686.5 g/mol
Synonyms	Man6GlcNAc2-Asn; High-Mannose Type N-Glycan; N-Glycan Core Pentasaccharide (Man6GlcNAc2); Asn-linked oligosaccharide; Glycan standard Man6GlcNAc2; Oligomannose-type glycan; N-Linked Glycan Reference Standard; (Man)6(GlcNAc)2-Asn
EINECS	Contact for details

Quality Control

Every batch of our (Mannose)6-(n-Acetylglucosamine)2-Asparagine is produced and analyzed under strict quality management protocols. We ensure high purity and structural integrity through comprehensive analytical techniques including NMR, Mass Spectrometry, and HPLC. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for complete traceability and compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.