Description

5-Hydroxyflufenamic Acid is a hydroxylated derivative of the non-steroidal anti-inflammatory drug (NSAID) flufenamic acid, serving as a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its role in the research and development of novel therapeutic agents, particularly those targeting inflammatory pathways. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel anti-inflammatory drug candidates and other bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop and optimize new chemical entities with enhanced therapeutic profiles.
• Biochemical Research: Serves as a tool compound for studying cyclooxygenase (COX) enzyme inhibition and related inflammatory mechanisms.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for introducing specific pharmacophores into complex molecular architectures.

Basic Information

Product Name	5-Hydroxyflufenamic Acid
CAS No.	39062-67-4
Molecular Formula	C14H10F3NO3
Molecular Weight	297.23 g/mol
Synonyms	2-[[3-(Trifluoromethyl)phenyl]amino]-5-hydroxybenzoic acid; 5-Hydroxy-N-(α,α,α-trifluoro-m-tolyl)anthranilic acid; 5-Hydroxyflufenamate; 5-OH-FA; Flufenamic acid, 5-hydroxy-; 2-[[3-(Trifluoromethyl)phenyl]amino]-5-hydroxy-benzoic acid
EINECS	Contact for details

Quality Control

Our 5-Hydroxyflufenamic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with detailed results to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The material is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.