Description

1-Bromo-2,4-Dimethyl-3-Nitrobenzene is a versatile halogenated aromatic compound that serves as a key synthetic intermediate in advanced organic chemistry. Its structure, featuring bromine and nitro substituents on a dimethylbenzene backbone, makes it a valuable electrophile for cross-coupling reactions and a precursor for more complex molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated aromatic core.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents where its substitution pattern is advantageous.
• Material Science Research: Serves as a monomer or precursor in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as an electrophilic partner in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Dye and Pigment Manufacturing: Employed as an intermediate in the synthesis of complex organic dyes and pigments.
• Academic and R&D Laboratories: Used in methodological studies and as a standard reagent for exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	1-Bromo-2,4-Dimethyl-3-Nitrobenzene
CAS No.	39053-43-5
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	2,4-Dimethyl-3-nitro-1-bromobenzene; 3-Nitro-1-bromo-2,4-dimethylbenzene; 1-Bromo-2,4-dimethyl-3-nitro-benzene; 2-Bromo-1,3-dimethyl-4-nitrobenzene; Benzene, 1-bromo-2,4-dimethyl-3-nitro-; 3-Nitro-2,4-dimethylbromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,4-Dimethyl-3-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.