Description

Phenyl α-L-Iduronide Cyclohexylammonium Salt is a high-purity biochemical reagent and synthetic intermediate of significant importance in glycoscience research and pharmaceutical development. This compound serves as a critical substrate and standard for studying enzyme kinetics, particularly for lysosomal enzymes like α-L-iduronidase, which is implicated in genetic disorders such as Mucopolysaccharidosis I. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in enzyme replacement therapy development and metabolic disease research.

Application

• Enzyme Activity Assays: Essential substrate for the in vitro determination of α-L-iduronidase activity in biological samples.
• Diagnostic Reagent Manufacturing: Key component in the production of kits for the diagnosis of lysosomal storage diseases, including Hurler, Scheie, and Hurler-Scheie syndromes (MPS I).
• Biochemical Research: Used as a standard and reference compound in glycosidase inhibition studies and carbohydrate metabolism research.
• Pharmaceutical Development: Employed as an intermediate in the synthesis of more complex glycoconjugates and potential therapeutic agents targeting glycosaminoglycan metabolism.
• Quality Control: Serves as a calibration standard in analytical laboratories for method validation and purity assessment of related compounds.

Basic Information

Product Name	Phenyl α-L-Iduronide Cyclohexylammonium Salt
CAS No.	39031-70-4
Molecular Formula	C18H27NO7 • C6H13N
Molecular Weight	469.51 g/mol
Synonyms	Phenyl α-L-Idopyranosiduronic Acid Cyclohexylammonium Salt; 4-Methylumbelliferyl α-L-Iduronide Analog (Phenyl); α-L-Iduronidase Substrate; Phenyl Iduronide; Cyclohexylammonium Phenyl α-L-Idopyranosiduronate; Phenyl-α-L-iduronide, Cyclohexylamine Salt; Iduronide Substrate for MPS I
EINECS	Contact for details

Quality Control

Our Phenyl α-L-Iduronide Cyclohexylammonium Salt is manufactured under controlled conditions to ensure high batch-to-batch consistency, which is critical for reproducible research and diagnostic results. Each lot undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR). A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Solubility	Soluble in water, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.