Description

(-)-Placodiolic Acid is a specific enantiomer of a lichen-derived depside compound. This chiral molecule is valued for its role as a key intermediate in organic synthesis and as a reference standard for analytical research. It is primarily utilized by research institutions and pharmaceutical development companies engaged in natural product chemistry, asymmetric synthesis, and bioactivity studies. The compound's defined stereochemistry is critical for applications requiring precise molecular interactions.

Application

• Pharmaceutical Research: Serves as a chiral building block or intermediate in the synthesis of novel bioactive compounds and potential drug candidates.
• Analytical Reference Standard: Used for method development, calibration, and quality control in HPLC, LC-MS, and other chromatographic analyses.
• Natural Product Chemistry: Employed as a pure, characterized compound for studying lichen metabolites, biosynthesis pathways, and structure-activity relationships (SAR).
• Asymmetric Synthesis: Acts as a starting material or model compound for developing new stereoselective catalytic reactions.
• Biochemical Studies: Investigated for its potential biological activities, including antimicrobial or enzyme inhibitory properties.
• Academic & Industrial R&D: Utilized in fundamental chemical research and development projects requiring high-purity, stereochemically defined intermediates.

Basic Information

Product Name	(-)-Placodiolic Acid
CAS No.	38965-63-8
Molecular Formula	C20H20O8
Molecular Weight	388.37 g/mol
Synonyms	Placodiolic Acid; (-)-Form of Placodiolic Acid; (R)-Placodiolic Acid; Lichesterinic acid related depside; 4-[(2,4-Dihydroxy-6-pentylbenzoyl)oxy]-2-hydroxy-6-methylbenzoic acid; 2,4-Dihydroxy-6-pentylbenzoic acid 4-carboxy-3-hydroxy-5-methylphenyl ester
EINECS	Contact for details

Quality Control

Our (-)-Placodiolic Acid is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, strength, and composition. A detailed Certificate of Analysis (COA) providing lot-specific results for assay, enantiomeric excess, and related substances is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.