Description

1-[(Aminooxy)Methyl]-4-Methylbenzene Hydrochloride is a specialized organic salt primarily used as a key synthetic intermediate and building block in advanced chemical synthesis. Its unique aminooxy functional group makes it a valuable reagent for the formation of oxime linkages, which are critical in bioconjugation, pharmaceutical development, and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for complex molecular construction.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring oxime or hydrazone functional groups.
• Bioconjugation Reagent: Used for linking biomolecules (e.g., proteins, antibodies) to drugs, dyes, or solid supports via stable oxime bonds in antibody-drug conjugates (ADCs) and diagnostic assays.
• Agrochemical Synthesis: Serves as an intermediate in the production of certain herbicides, fungicides, and plant growth regulators.
• Polymer Modification: Employed to introduce reactive aminooxy sites into polymer chains for cross-linking or functionalization to create advanced materials.
• Chemical Biology Research: A valuable tool for chemoselective ligation strategies in probe development and studying biomolecular interactions.
• Crosslinking Agent: Acts as a linker molecule in the preparation of hydrogels, resins, and other cross-linked polymeric networks.

Basic Information

Product Name	1-[(Aminooxy)Methyl]-4-Methylbenzene Hydrochloride
CAS No.	38936-62-8
Molecular Formula	C8H12ClNO
Molecular Weight	173.64 g/mol
Synonyms	4-Methylbenzylaminooxy Hydrochloride; p-Tolylmethoxyamine Hydrochloride; (Aminooxymethyl)-4-methylbenzene Hydrochloride; 1-(Aminooxymethyl)-4-methylbenzene Hydrochloride; 4-Methylbenzaldehyde O-(Aminomethyl)oxime Hydrochloride; Aminooxy-p-xylene Hydrochloride; p-Xylyleneaminooxy Hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[(Aminooxy)Methyl]-4-Methylbenzene Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters including assay (HPLC), identification (IR, NMR), and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates, including cGMP manufacturing for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.