Description

1-Bromo-2-Prop-2-Ynoxy-Benzene is a specialized aromatic building block featuring both bromine and propargyl ether functional groups. This unique bifunctional structure makes it a valuable intermediate for advanced organic synthesis, particularly in constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides requiring specific aromatic ether linkages.
• Material Science Research: Serves as a monomer or precursor in the development of advanced polymers and functional organic materials.
• Cross-Coupling Reactions: The bromine atom is an effective handle for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira), while the alkyne group enables click chemistry.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis and organocatalysts.
• Academic & Industrial R&D: A versatile reagent for methodological studies and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	1-Bromo-2-Prop-2-Ynoxy-Benzene
CAS No.	38770-76-2
Molecular Formula	C9H7BrO
Molecular Weight	211.06 g/mol
Synonyms	2-Bromophenyl propargyl ether; 1-Bromo-2-(prop-2-yn-1-yloxy)benzene; o-Bromophenyl propargyl ether; Propargyl 2-bromophenyl ether; 2-Bromo-1-(prop-2-ynyloxy)benzene; Benzene, 1-bromo-2-(2-propynyloxy)-
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Prop-2-Ynoxy-Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles against our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.