Description

Methanesulfonic Acid, (1R,2R)-2-Phenylcyclohexan-1-Amine is a high-purity chiral amine salt, specifically designed for advanced synthetic applications. This compound is valued for its role as a key chiral intermediate and resolving agent in the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drugs.
• Chiral Resolution Agent: Used to separate enantiomers of racemic mixtures in process chemistry and analytical method development.
• Catalyst and Ligand Precursor: Serves as a precursor for chiral catalysts and ligands used in asymmetric synthesis.
• Agrochemical Synthesis: Employed in the research and development of enantiomerically pure herbicides and pesticides.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research.
• Fine Chemical Production: Used in the manufacture of specialty chemicals requiring high stereochemical fidelity.

Basic Information

Product Name	Methanesulfonic Acid, (1R,2R)-2-Phenylcyclohexan-1-Amine
CAS No.	38727-05-8
Molecular Formula	C13H19NO3S
Molecular Weight	269.36 g/mol
Synonyms	(1R,2R)-2-Phenylcyclohexanamine methanesulfonate; (1R,2R)-2-Phenylcyclohexylamine methanesulfonate; (1R,2R)-(-)-2-Phenylcyclohexylamine methanesulfonate salt; (1R,2R)-1-Amino-2-phenylcyclohexane methanesulfonate; (1R,2R)-trans-2-Phenylcyclohexylamine methanesulfonic acid salt; (1R,2R)-PCA methanesulfonate; (1R,2R)-2-PCA mesylate
EINECS	Contact for details

Quality Control

Our Methanesulfonic Acid, (1R,2R)-2-Phenylcyclohexan-1-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for chiral intermediates. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.